The open DOME is a project created at the University of Bristol by Ana Rubio Denniss, Dr. Thomas Gorochowski and Dr. Sabine Hauert.

Subsequently, two PhD projects have been created to further study spatiotemporal control of different micro-agents inside the DOME. The researchers are Matthew Uppington and Neshika Wijewardhane.

The DOME allows for localised optical interaction with microscale agents such as bacteria, living and synthetic cells, microparticles, and algae.

A closed-loop computational set-up running on two networked Raspberry Pi computers allows for the running of automated control scripts, such that the optical micro-environment is shaped around the evolving dynamics of the system.

Multi-wavelength illumination at 455, 517 and 632nm can be delivered by the native projector to the sample with 30×30µm resolution. Illuminations have also been conducted at 405 and 530nm using custom LEDs with light directed into the projector.

A more detailed overview and characterisation of the DOME is available in a number of our papers, bitbucket repositories and in the Build your own DOME section here on the website.